Biologics target very specific areas in the body to treat diseases.

This means they can often work better and have fewer side effects compared to other immunosuppressive drugs (e.g., methotrexate and azathioprine)5 or therapies that suppress a broad range of cytokines (e.g., Janus kinase inhibitors).9,10

Visit the link below to discover how biologics are changing the landscape of atopic dermatitis treatment.

Biologics In Depth

REFERENCES:

  1. U.S. Food & Drug Administration. (2018). What are “biologics" questions and answers. https://www.fda.gov/about-fda/center-biologics-evaluation-and-research-cber/what-are-biologics-questions-and-answers. (Accessed March 23, 2024).
  2. World Health Organization. Biologicals. https://www.who.int/health-topics/biologicals#tab=tab_1. (Accessed March 23, 2024).
  3. Adami, G., Saag, K. G., Chapurlat, R. D., et al. (2019). Balancing benefits and risks in the era of biologics. Ther Adv Musculoskelet Dis, 11, 1759720X19883973.
  4. Morrow, T., & Felcone, L. H. (2004). Defining the di erence: What makes biologics unique. Biotechnol Healthc, 1(4), 24-29.
  5. Raychaudhuri, S. P., & Raychaudhuri, S. K. (2009). Biologics: Target-specific treatment of systemic and cutaneous autoimmune diseases. Indian J Dermatol, 54(2), 100-109.
  6. Veilleux, M. S., & Shear, N. H. (2017). Biologics in patients with skin diseases. J Allergy Clin Immunol, 139(5), 1423-1430.
  7. Papiez, M. A., & Krzysciak, W. (2021). Biological therapies in the treatment of cancer - update and new directions. Int J Mol Sci, 22(21), 11694.
  8. McGregor, M. C., Krings, J. G., Nair, P., & Castro, M. (2019). Role of biologics in asthma. Am J Respir Crit Care Med, 199(4), 433-445.
  9. Alten, R., Mischkewitz, M., Stefanski, A. L., & Dörner, T. (2020). Janus kinase inhibitors : State of the art in clinical use and future perspectives. Z Rheumatol, 79(3), 241-254.
  10. Butala, S., Castelo-Soccio, L., Seshadri, R., et al. (2023). Biologic versus small molecule therapy for treating moderate to severe atopic dermatitis: Clinical considerations. J Allergy Clin Immunol Pract, 11(5), 1361-1373.

Health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

MAT-SG-2400085-1.0-04/2024